Ecology and Evolutionary Biology
333 Biosciences West
1041 E. Lowell
University of Arizona
Tucson, AZ 85721
Tel: (520) 626-4747
FAX: (520) 621-9190
E-mail: geraldes@email.arizona.edu

The ultimate goal of biology is to understand how variation at the genomic level translates into phenotypic variation within and between species. My current and past research aims at understanding how nucleotide variation is partitioned within and among species and how this partitioning is affected by genomic context and natural history. For my PhD I worked on the genetics of speciation in Oryctolagus cuniculus (European rabbit), by comparing patterns of introgression at different loci (namely, mtDNA, Y and X-linked loci) across a hybrid zone. For my post doctoral work I am taking a similar approach to understand the genetics of speciation in house mice. I am assembling a large polymorphism data set in three species of house mice (Mus domesticus, M. musculus and M. castaneus). We will use this data set to compare levels and patterns of polymorphism and divergence (i) at autosomal, X and Y-linked and mitochondrial loci and, (ii) in autosomal regions of the genome with significant differences in recombination rates.

PUBLICATIONS

Geraldes, A., Carneiro, M., Delibes-Mateos, M., Villafuerte, R., Nachman, M. W., and Ferrand, N. (in press) Reduced introgression of the Y chromosome between subspecies of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula. Molecular Ecology.

Geraldes, A., Basset, P., Gibson, B., Smith, K., Harr, B., Yu, H. T., Bulatova, N., Ziv, Y., and Nachman, M. W. (in press) Inferring the history of speciation in house mice from autosomal, X-linked, Y-linked and mitochondrial genes. Molecular Ecology.

Salcedo, T., Geraldes, A., and Nachman, M. W. 2007. Nucleotide variation in wild and inbred mice. Genetics, 177: 2277-2291.

Geraldes, A., Ferrand, N. and Nachman, M. W. 2006. Contrasting patterns of introgression at X-linked loci across the hybrid zone between subspecies of the European rabbit (Oryctolagus cuniculus). Genetics, 173: 919-933.

Geraldes, A. and Ferrand, N. 2006. A 7-bp insertion in the 3' untranslated region suggests the duplication and concerted evolution of the rabbit Sry gene. Genetics Selection and Evolution, 38: 313-320.

Geraldes, A., Rogel-Gaillard, C. and Ferrand, N. 2005. High levels of nucleotide diversity in the European rabbit (Oryctolagus cuniculus) SRY gene. Animal Genetics, 36: 349-351.